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During the period of 10.6 years from January, 1974 to June, 1984, clinical observations were made en 28 patients with multiple urothelial tumors involving 2 or more sites among renal pelvis, ureter, bladder and urethra. Out of 28 patients 1 multiple urothelial tumors, 7 had renal pelvis and ureteral tumor, 12 had upper urinary tract and bladder tumor, and 9 had bladder and urethral tumor. The results were as follows 1. 7 patients c renal pelvis and concomitant ureter tumor mostly had higher grade and higher stage tumors. 2. 12 patients c upper urinary tract and concomitant or subsequent development of bladder tumor usually had higher grade and higher stage tumors. 3. Patients having bladder tumor c urethral tumor showed multiple bladder tumors in 8 out of 9 cases, bladder neck lesion were in 7 of 9 cases. The location of urethral tumors showed 2 cases at anterior urethra and 8 cases at posterior urethra. The shape of urethral tumors showed papillary type in 3 cases and non-papillary type in 5 cases.
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